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Increased RhoA Prenylation in the loechrig (loe) Mutant Leads to Progressive Neurodegeneration
The Drosophila mutant loechrig (loe) shows age-dependent degeneration of the nervous system and is caused by the loss of a neuronal isoform of the AMP-activated protein kinase (AMPK) γ-subunit (also known as SNF4Aγ). The trimeric AMPK complex is activated by low energy levels and metabolic insults a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3435293/ https://ncbi.nlm.nih.gov/pubmed/22970217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044440 |
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