Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques

Targeting Mycobacterium tuberculosis bacilli in low-oxygen microenvironments, such as caseous granulomas, has been hypothesized to have the potential to shorten therapy for active tuberculosis (TB) and prevent reactivation of latent infection. We previously reported that upon low-dose M. tuberculosi...

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Detalhes bibliográficos
Main Authors: Lin, Philana Ling, Dartois, Veronique, Johnston, Paul J., Janssen, Christopher, Via, Laura, Goodwin, Michael B., Klein, Edwin, Barry, Clifton E., Flynn, JoAnne L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435210/
https://ncbi.nlm.nih.gov/pubmed/22826237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121497109
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