The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection

It is estimated that one-third of the world’s population is infected with Mycobacterium tuberculosis. Infection typically remains latent, but it can reactivate to cause clinical disease. The only vaccine, Mycobacterium bovis bacillus Calmette-Guérin (BCG), is largely ineffective, and ways to enhance...

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Detalhes bibliográficos
Main Authors: Lin, Philana Ling, Dietrich, Jes, Tan, Esterlina, Abalos, Rodolfo M., Burgos, Jasmin, Bigbee, Carolyn, Bigbee, Matthew, Milk, Leslie, Gideon, Hannah P., Rodgers, Mark, Cochran, Catherine, Guinn, Kristi M., Sherman, David R., Klein, Edwin, Janssen, Christopher, Flynn, JoAnne L., Andersen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248283/
https://ncbi.nlm.nih.gov/pubmed/22133873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46252
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