The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection

It is estimated that one-third of the world’s population is infected with Mycobacterium tuberculosis. Infection typically remains latent, but it can reactivate to cause clinical disease. The only vaccine, Mycobacterium bovis bacillus Calmette-Guérin (BCG), is largely ineffective, and ways to enhance...

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Main Authors: Lin, Philana Ling, Dietrich, Jes, Tan, Esterlina, Abalos, Rodolfo M., Burgos, Jasmin, Bigbee, Carolyn, Bigbee, Matthew, Milk, Leslie, Gideon, Hannah P., Rodgers, Mark, Cochran, Catherine, Guinn, Kristi M., Sherman, David R., Klein, Edwin, Janssen, Christopher, Flynn, JoAnne L., Andersen, Peter
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2011
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248283/
https://ncbi.nlm.nih.gov/pubmed/22133873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46252
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