Evidence for DNA-Binding Domain–Ligand-Binding Domain Communications in the Androgen Receptor

DNA binding as well as ligand binding by nuclear receptors has been studied extensively. Both binding functions are attributed to isolated domains of which the structure is known. The crystal structure of a complete receptor in complex with its ligand and DNA-response element, however, has been solv...

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Bibliographic Details
Main Authors: Helsen, Christine, Dubois, Vanessa, Verfaillie, Annelien, Young, Jacques, Trekels, Mieke, Vancraenenbroeck, Renée, De Maeyer, Marc, Claessens, Frank
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434514/
https://ncbi.nlm.nih.gov/pubmed/22645304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00151-12
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