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LBD Dimerization of the Androgen Receptor but Not N/C Interaction Is Crucial for Normal Male Development in Mice

The androgen receptor (AR) is a nuclear receptor with a main role in the development and maintenance of the male phenotype. To execute its role as transcription factor, the AR forms homodimers. Three dimerization modes have been described for the AR: one via the DNA binding domain, a second via the...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: El Kharraz, Sarah, Helsen, Christine, Dubois, Vanessa, Libert, Claude, Poutanen, Matti, Claessens, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089729/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1675
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