Androgen Regulation of the TMPRSS2 Gene and the Effect of a SNP in an Androgen Response Element

More than 50% of prostate cancers have undergone a genomic reorganization that juxtaposes the androgen-regulated promoter of TMPRSS2 and the protein coding parts of several ETS oncogenes. These gene fusions lead to prostate-specific and androgen-induced ETS expression and are associated with aggress...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Clinckemalie, Liesbeth, Spans, Lien, Dubois, Vanessa, Laurent, Michaël, Helsen, Christine, Joniau, Steven, Claessens, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426606/
https://ncbi.nlm.nih.gov/pubmed/24109594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1098
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