Structure of the homodimeric androgen receptor ligand-binding domain

The androgen receptor (AR) plays a crucial role in normal physiology, development and metabolism as well as in the aetiology and treatment of diverse pathologies such as androgen insensitivity syndromes (AIS), male infertility and prostate cancer (PCa). Here we show that dimerization of AR ligand-bi...

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Udgivet i:Nat Commun
Main Authors: Nadal, Marta, Prekovic, Stefan, Gallastegui, Nerea, Helsen, Christine, Abella, Montserrat, Zielinska, Karolina, Gay, Marina, Vilaseca, Marta, Taulès, Marta, Houtsmuller, Adriaan B., van Royen, Martin E., Claessens, Frank, Fuentes-Prior, Pablo, Estébanez-Perpiñá, Eva
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303882/
https://ncbi.nlm.nih.gov/pubmed/28165461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14388
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