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Telomerase Recruitment Requires both TCAB1 and Cajal Bodies Independently
The ability of most cancer cells to grow indefinitely relies on the enzyme telomerase and its recruitment to telomeres. In human cells, recruitment depends on the Cajal body RNA chaperone TCAB1 binding to the RNA subunit of telomerase (hTR) and is also thought to rely on an N-terminal domain of the...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434490/ https://ncbi.nlm.nih.gov/pubmed/22547674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00379-12 |
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