iTRAQ Labeling is Superior to mTRAQ for Quantitative Global Proteomics and Phosphoproteomics

Labeling of primary amines on peptides with reagents containing stable isotopes is a commonly used technique in quantitative mass spectrometry. Isobaric labeling techniques such as iTRAQ™ or TMT™ allow for relative quantification of peptides based on ratios of reporter ions in the low m/z region of...

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Bibliografske podrobnosti
Main Authors: Mertins, Philipp, Udeshi, Namrata D., Clauser, Karl R., Mani, DR, Patel, Jinal, Ong, Shao-en, Jaffe, Jacob D., Carr, Steven A.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2012
Teme:
Technological Innovation and Resources
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433912/
https://ncbi.nlm.nih.gov/pubmed/22210691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.014423
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