Quantitative phosphoproteomic analysis of neuronal intermediate filament proteins (NF-M/H) in Alzheimer's disease by iTRAQ

Aberrant hyperphosphorylation of neuronal cytoskeletal proteins is one of the major pathological hallmarks of neurodegenerative disorders such as Alzheimer disease (AD), amyotrophic lateral sclerosis (ALS), and Parkinson's disease (PD). Human NF-M/H display a large number of multiple KSP repeat...

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Main Authors: Rudrabhatla,*, Parvathi, Grant,*, Philip, Jaffe, Howard, Strong, Michael J., Pant, Harish C.
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2010
Teme:
Research Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974420/
https://ncbi.nlm.nih.gov/pubmed/20624930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-157859
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