Quantitative phosphoproteomic analysis of neuronal intermediate filament proteins (NF-M/H) in Alzheimer's disease by iTRAQ

Aberrant hyperphosphorylation of neuronal cytoskeletal proteins is one of the major pathological hallmarks of neurodegenerative disorders such as Alzheimer disease (AD), amyotrophic lateral sclerosis (ALS), and Parkinson's disease (PD). Human NF-M/H display a large number of multiple KSP repeat...

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Detalhes bibliográficos
Main Authors: Rudrabhatla,*, Parvathi, Grant,*, Philip, Jaffe, Howard, Strong, Michael J., Pant, Harish C.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2010
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974420/
https://ncbi.nlm.nih.gov/pubmed/20624930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-157859
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