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Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer's NFTs

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by brain pathology of intracellular neurofibrillary tangles (NFTs) and extracellular amyloid plaques. NFTs contain aberrantly hyperphosphorylated Tau as paired helical filaments (PHFs). Although NFs have been shown immunohis...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Rudrabhatla, Parvathi, Jaffe, Howard, Pant, Harish C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Federation of American Societies for Experimental Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205835/
https://ncbi.nlm.nih.gov/pubmed/21828286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-181297
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