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Alzheimer neurofibrillary tangles contain phosphorylated and hidden neurofilament epitopes.

Three monoclonal antibodies to neurofilaments (RT97, BF10 and 147), two of which also recognised neurofibrillary tangles (RT97 and BF10), have all been shown to be specific for phosphorylated epitopes. Treatment of histological sections with alkaline phosphatase prior to immunostaining resulted in r...

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Bibliographic Details
Published in:J Neurol Neurosurg Psychiatry
Main Authors: Haugh, M C, Probst, A, Ulrich, J, Kahn, J, Anderton, B H
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 1986
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1029067/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2432188/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jnnp.49.11.1213
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