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Alzheimer neurofibrillary tangles contain phosphorylated and hidden neurofilament epitopes.

Three monoclonal antibodies to neurofilaments (RT97, BF10 and 147), two of which also recognised neurofibrillary tangles (RT97 and BF10), have all been shown to be specific for phosphorylated epitopes. Treatment of histological sections with alkaline phosphatase prior to immunostaining resulted in r...

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Bibliografiske detaljer
Udgivet i:J Neurol Neurosurg Psychiatry
Principais autores: Haugh, M C, Probst, A, Ulrich, J, Kahn, J, Anderton, B H
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 1986
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1029067/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2432188/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jnnp.49.11.1213
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