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Alzheimer neurofibrillary tangles contain phosphorylated and hidden neurofilament epitopes.
Three monoclonal antibodies to neurofilaments (RT97, BF10 and 147), two of which also recognised neurofibrillary tangles (RT97 and BF10), have all been shown to be specific for phosphorylated epitopes. Treatment of histological sections with alkaline phosphatase prior to immunostaining resulted in r...
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| Publicado no: | J Neurol Neurosurg Psychiatry |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1029067/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2432188/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jnnp.49.11.1213 |
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