Quantitative phosphoproteomic analysis of neuronal intermediate filament proteins (NF-M/H) in Alzheimer's disease by iTRAQ

Aberrant hyperphosphorylation of neuronal cytoskeletal proteins is one of the major pathological hallmarks of neurodegenerative disorders such as Alzheimer disease (AD), amyotrophic lateral sclerosis (ALS), and Parkinson's disease (PD). Human NF-M/H display a large number of multiple KSP repeat...

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Auteurs principaux: Rudrabhatla,*, Parvathi, Grant,*, Philip, Jaffe, Howard, Strong, Michael J., Pant, Harish C.
Format: Artigo
Langue:Inglês
Publié: Federation of American Societies for Experimental Biology 2010
Sujets:
Research Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974420/
https://ncbi.nlm.nih.gov/pubmed/20624930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-157859
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