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Metabolic acidosis increases fibroblast growth factor 23 in neonatal mouse bone
Fibroblast growth factor 23 (FGF23) significantly increases with declining renal function, leading to reduced renal tubular phosphate reabsorption, decreased 1,25-dihydroxyvitamin D, and increased left ventricular hypertrophy. Elevated FGF23 is associated with increased mortality. FGF23 is synthesiz...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433868/ https://ncbi.nlm.nih.gov/pubmed/22647635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00199.2012 |
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