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Metabolic acidosis increases fibroblast growth factor 23 in neonatal mouse bone

Fibroblast growth factor 23 (FGF23) significantly increases with declining renal function, leading to reduced renal tubular phosphate reabsorption, decreased 1,25-dihydroxyvitamin D, and increased left ventricular hypertrophy. Elevated FGF23 is associated with increased mortality. FGF23 is synthesiz...

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Detalhes bibliográficos
Main Authors: Krieger, Nancy S., Culbertson, Christopher D., Kyker-Snowman, Kelly, Bushinsky, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433868/
https://ncbi.nlm.nih.gov/pubmed/22647635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00199.2012
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