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Lyn kinase mediates cell motility and tumor growth in EGFRvIII-expressing head and neck cancer

PURPOSE: Epidermal growth factor receptor variant 3 (EGFRvIII) has been detected in several cancers where tumors expressing this truncated growth factor receptor demonstrate more aggressive behavior. The molecular mechanisms that contribute to EGFRvIII-mediated tumor progression that are amenable to...

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Autors principals: Wheeler, S.E., Morariu, E.M., Bednash, J.S., Otte, C.G., Seethala, R.R., Chiosea, S.I., Grandis, J.R.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433855/
https://ncbi.nlm.nih.gov/pubmed/22490227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2486
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