Challenges in EGFRvIII Detection in Head and Neck Squamous Cell Carcinoma

OBJECTIVE: Head and neck squamous cell carcinoma (HNSCC) accounts for more than 5% of all cancers worldwide. The mortality rate of HNSCC has remained unchanged (approximately 50%) over the last few decades. Ubiquitous overexpression of wild type EGFR in many solid tumors has led to the development o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wheeler, Sarah E., Egloff, Ann Marie, Wang, Lin, James, C. David, Hammerman, Peter S., Grandis, Jennifer R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320077/
https://ncbi.nlm.nih.gov/pubmed/25658924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117781
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