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Molecular chaperones regulate p53 and suppress senescence programs
Many types of cancer cells constitutively express major molecular chaperones at high levels. Recent findings demonstrate that specific depletion of individual chaperones, including various members of the Hsp70 family, small heat shock proteins, or VCP/p97, leads to activation of p53 pathway and subs...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433766/ https://ncbi.nlm.nih.gov/pubmed/17555746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.05.036 |
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