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Heat Shock Protein Hsp72 Controls Oncogene-Induced Senescence Pathways in Cancer Cells

The heat shock protein Hsp72 is expressed at the elevated levels in various human tumors, and its levels often correlate with poor prognosis. Previously we reported that knockdown of Hsp72 in certain cancer cells, but not in untransformed breast epithelial cells, triggers senescence via p53-dependen...

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Hlavní autoři: Gabai, Vladimir L., Yaglom, Julia A., Waldman, Todd, Sherman, Michael Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612502/
https://ncbi.nlm.nih.gov/pubmed/19001088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01041-08
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