Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections

Susceptibility to tuberculosis is historically ascribed to an inadequate immune response that fails to control infecting mycobacteria. In zebrafish, we find that susceptibility to Mycobacterium marinum can result from either inadequate or excessive acute inflammation. Modulation of the leukotriene A...

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Bibliographische Detailangaben
Hauptverfasser: Tobin, David M., Roca, Francisco J., Oh, Sungwhan F., McFarland, Ross, Vickery, Thad W., Ray, John P., Ko, Dennis C., Zou, Yuxia, Bang, Nguyen D., Chau, Tran T. H., Vary, Jay C., Hawn, Thomas R., Dunstan, Sarah J., Farrar, Jeremy J., Thwaites, Guy E., King, Mary-Claire, Serhan, Charles N., Ramakrishnan, Lalita
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433720/
https://ncbi.nlm.nih.gov/pubmed/22304914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.12.023
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