The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans

Exposure to Mycobacterium tuberculosis produces varied early outcomes, ranging from resistance to infection to progressive disease. Here we report results from a forward genetic screen in zebrafish larvae that identify multiple mutant classes with distinct patterns of innate susceptibility to Mycoba...

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Bibliografiske detaljer
Main Authors: Tobin, David M., Vary, Jay C., Ray, John P., Walsh, Gregory S., Dunstan, Sarah J., Bang, Nguyen D., Hagge, Deanna A., Khadge, Saraswoti, King, Mary-Claire, Hawn, Thomas R., Moens, Cecilia B., Ramakrishnan, Lalita
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907082/
https://ncbi.nlm.nih.gov/pubmed/20211140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.02.013
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