The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans

Exposure to Mycobacterium tuberculosis produces varied early outcomes, ranging from resistance to infection to progressive disease. Here we report results from a forward genetic screen in zebrafish larvae that identify multiple mutant classes with distinct patterns of innate susceptibility to Mycoba...

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Hlavní autoři: Tobin, David M., Vary, Jay C., Ray, John P., Walsh, Gregory S., Dunstan, Sarah J., Bang, Nguyen D., Hagge, Deanna A., Khadge, Saraswoti, King, Mary-Claire, Hawn, Thomas R., Moens, Cecilia B., Ramakrishnan, Lalita
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907082/
https://ncbi.nlm.nih.gov/pubmed/20211140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.02.013
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