The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans

Exposure to Mycobacterium tuberculosis produces varied early outcomes, ranging from resistance to infection to progressive disease. Here we report results from a forward genetic screen in zebrafish larvae that identify multiple mutant classes with distinct patterns of innate susceptibility to Mycoba...

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Detalhes bibliográficos
Main Authors: Tobin, David M., Vary, Jay C., Ray, John P., Walsh, Gregory S., Dunstan, Sarah J., Bang, Nguyen D., Hagge, Deanna A., Khadge, Saraswoti, King, Mary-Claire, Hawn, Thomas R., Moens, Cecilia B., Ramakrishnan, Lalita
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907082/
https://ncbi.nlm.nih.gov/pubmed/20211140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.02.013
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