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Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections
Susceptibility to tuberculosis is historically ascribed to an inadequate immune response that fails to control infecting mycobacteria. In zebrafish, we find that susceptibility to Mycobacterium marinum can result from either inadequate or excessive acute inflammation. Modulation of the leukotriene A...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433720/ https://ncbi.nlm.nih.gov/pubmed/22304914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.12.023 |
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