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Human TOLLIP regulates TLR2 and TLR4 signaling and its polymorphisms are associated with susceptibility to tuberculosis

Tuberculosis, one of the leading causes of death worldwide, stimulates inflammatory responses with beneficial and pathologic consequences. The regulation and nature of an optimal inflammatory response to Mycobacterium tuberculosis (MTb) remains poorly understood in humans. Insight into mechanisms of...

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Detalhes bibliográficos
Main Authors: Shah, Javeed A, Vary, Jay C, Chau, Tran TH, Bang, Nguyen D, Yen, Nguyen TB, Farrar, Jeremy J, Dunstan, Sarah J, Hawn, Thomas R
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428135/
https://ncbi.nlm.nih.gov/pubmed/22778396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103541
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