A Polymorphism in Human CD1A is Associated with Susceptibility to Tuberculosis

CD1 proteins are antigen-presenting molecules that evolved to present lipids rather than peptides to T cells. However, unlike major histocompatibility complex genes, CD1 genes show low rates of polymorphism and have not been clearly associated with human disease. We report that an intronic polymorph...

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Main Authors: Seshadri, Chetan, Thuong, Nguyen Thuy Thuong, Yen, Nguyen Thi Bich, Bang, Nguyen Duc, Chau, Tran Thi Hong, Thwaites, Guy E., Dunstan, Sarah J., Hawn, Thomas R.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998877/
https://ncbi.nlm.nih.gov/pubmed/24500401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2014.5
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