Common Polymorphisms in the CD43 Gene Region Are Associated with Tuberculosis Disease and Mortality

CD43, a surface glycoprotein, regulates Mycobacterium tuberculosis macrophage binding, replication, and proinflammatory cytokine induction in a murine model. We hypothesized that single-nucleotide polymorphisms (SNPs) in the CD43 gene region are associated with human tuberculosis (TB) susceptibility...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Campo, Monica, Randhawa, April K., Dunstan, Sarah, Farrar, Jeremy, Caws, Maxine, Bang, Nguyen Duc, Lan, Nguyen Ngoc, Hong Chau, Tran Thi, Horne, David J., Thuong, Nguyen Thuong, Thwaites, Guy E., Hawn, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370260/
https://ncbi.nlm.nih.gov/pubmed/25078322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0114OC
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