Common Polymorphisms in the CD43 Gene Region Are Associated with Tuberculosis Disease and Mortality

CD43, a surface glycoprotein, regulates Mycobacterium tuberculosis macrophage binding, replication, and proinflammatory cytokine induction in a murine model. We hypothesized that single-nucleotide polymorphisms (SNPs) in the CD43 gene region are associated with human tuberculosis (TB) susceptibility...

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Détails bibliographiques
Publié dans:Am J Respir Cell Mol Biol
Auteurs principaux: Campo, Monica, Randhawa, April K., Dunstan, Sarah, Farrar, Jeremy, Caws, Maxine, Bang, Nguyen Duc, Lan, Nguyen Ngoc, Hong Chau, Tran Thi, Horne, David J., Thuong, Nguyen Thuong, Thwaites, Guy E., Hawn, Thomas R.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2015
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370260/
https://ncbi.nlm.nih.gov/pubmed/25078322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0114OC
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