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Revisiting Oxytocin Through the Medium of Isonitriles
The reaction of thioamino acids and N-terminal peptides, mediated by hindered isonitriles and HOBt, gives rise to peptide bonds. In one pathway, oxytocin was synthesized by eight such reiterative amidations. In another stereospecific track, oxytocin was constructed by native chemical ligation, where...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433685/ https://ncbi.nlm.nih.gov/pubmed/22830449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3063452 |
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