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Enhancing the Scope of the Diels-Alder Reaction through Isonitrile Chemistry: Emergence of a New Class of Acyl-Activated Dienophiles

α,β-Unsaturated imides, formylated at the nitrogen atom, comprise a new and valuable family of dienophiles for servicing Diels-Alder reactions. These systems are assembled through extension of recently discovered isonitrile chemistry to the domain of α,β-unsaturated acids. Cycloadditions are facilit...

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Detalhes bibliográficos
Main Authors: Townsend, Steven D., Wu, Xiangyang, Danishefsky, Samuel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396883/
https://ncbi.nlm.nih.gov/pubmed/22708980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja303876e
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