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Direct observation of mammalian cell growth and size regulation
We introduce a microfluidic system for simultaneously measuring single cell mass and cell cycle progression over multiple generations. We use this system to obtain over 1,000 hours of growth data from mouse lymphoblast and pro-B-cell lymphoid cell lines. Cell lineage analysis revealed a decrease in...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433595/ https://ncbi.nlm.nih.gov/pubmed/22863882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2133 |
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