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Direct observation of mammalian cell growth and size regulation

We introduce a microfluidic system for simultaneously measuring single cell mass and cell cycle progression over multiple generations. We use this system to obtain over 1,000 hours of growth data from mouse lymphoblast and pro-B-cell lymphoid cell lines. Cell lineage analysis revealed a decrease in...

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Detalhes bibliográficos
Main Authors: Son, Sungmin, Tzur, Amit, Weng, Yaochung, Jorgensen, Paul, Kim, Jisoo, Kirschner, Marc W., Manalis, Scott R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433595/
https://ncbi.nlm.nih.gov/pubmed/22863882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2133
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