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Cell Growth and Size Homeostasis in Proliferating Animal Cells

A longstanding question in biology is whether there is an intrinsic mechanism for coordinating growth and cell cycle in metazoan cells. We have examined cell size distributions in populations of lymphoblasts and applied a novel mathematical analysis to calculate accurately how growth rates vary with...

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Autors principals: Tzur, Amit, Kafri, Ran, LeBleu, Valerie S., Lahav, Galit, Kirschner, Marc, W.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905160/
https://ncbi.nlm.nih.gov/pubmed/19589995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1174294
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