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YAP regulates cell size and growth dynamics via non-cell autonomous mediators

The Hippo pathway regulates organ size, regeneration, and cell growth by controlling the stability of the transcription factor, YAP (Yorkie in Drosophila). When there is tissue damage, YAP is activated allowing the restoration of homeostatic tissue size. The exact signals by which YAP is activated a...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Mugahid, Douaa, Kalocsay, Marian, Liu, Xili, Gruver, Jonathan Scott, Peshkin, Leonid, Kirschner, Marc W
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989120/
https://ncbi.nlm.nih.gov/pubmed/31913124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53404
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