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YAP regulates cell size and growth dynamics via non-cell autonomous mediators

The Hippo pathway regulates organ size, regeneration, and cell growth by controlling the stability of the transcription factor, YAP (Yorkie in Drosophila). When there is tissue damage, YAP is activated allowing the restoration of homeostatic tissue size. The exact signals by which YAP is activated a...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Mugahid, Douaa, Kalocsay, Marian, Liu, Xili, Gruver, Jonathan Scott, Peshkin, Leonid, Kirschner, Marc W
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989120/
https://ncbi.nlm.nih.gov/pubmed/31913124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53404
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