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Gr-1+CD11b+ cells are responsible for tumor promoting effect of TGF-β in breast cancer progression

One great challenge in our understanding of TGF-β cancer biology and the successful application of TGF-β targeted therapy is that TGF-β works as both a tumor suppressor and a tumor promoter. The underlying mechanisms for its functional change remain to be elucidated. Using 4T1 mammary tumor model th...

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Bibliographic Details
Main Authors: Li, Zhaoyang, Pang, Yanli, Gara, Sudheer Kumar, Achyut, B.R., Heger, Christopher, Goldsmith, Paul K., Lonning, Scott, Yang, Li
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433574/
https://ncbi.nlm.nih.gov/pubmed/22487809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27572
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