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TGF-β and immune cells: an important regulatory axis in the tumor microenvironment and progression

Transforming growth factor β (TGF-β) plays an important role in tumor initiation and progression, functioning as both a suppressor and a promoter. The mechanisms underlying this dual role of TGF-β remain unclear. TGF-β exerts systemic immune suppression and inhibits host immunosurveillance. Neutrali...

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Bibliografiske detaljer
Main Authors: Yang, Li, Pang, Yanli, Moses, Harold L.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891151/
https://ncbi.nlm.nih.gov/pubmed/20538542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2010.04.002
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