Transforming growth factor β signaling in myeloid cells is required for tumor metastasis

TGFβ is over expressed in advanced human cancers. It correlates with metastasis and poor prognosis. However, TGFβ functions as both a tumor suppressor and a tumor promoter. Here we report for the first time that genetic deletion of Tgfbr2 specifically in myeloid cells (Tgfbr2(MyeKO)) significantly i...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Pang, Yanli, Gara, Sudheer Kumar, Achyut, Bhagelu R., Li, Zhaoyang, Yan, Hannah H., Day, Chi-Ping, Weiss, Jonathan M., Trinchieri, Giorgio, Morris, John C., Yang, Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678771/
https://ncbi.nlm.nih.gov/pubmed/23661553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0527
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