ICAM-1–activated Src and eNOS signaling increase endothelial cell surface PECAM-1 adhesivity and neutrophil transmigration

Polymorphonuclear neutrophil (PMN) extravasation requires selectin-mediated tethering, intercellular adhesion molecule-1 (ICAM-1)–dependent firm adhesion, and platelet/endothelial cell adhesion molecule 1 (PECAM-1)–mediated transendothelial migration. An important unanswered question is whether ICAM...

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Detalhes bibliográficos
Main Authors: Liu, Guoquan, Place, Aaron T., Chen, Zhenlong, Brovkovych, Viktor M., Vogel, Stephen M., Muller, William A., Skidgel, Randal A., Malik, Asrar B., Minshall, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433096/
https://ncbi.nlm.nih.gov/pubmed/22806890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-397430
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