Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1–VE-cadherin interaction

Intercellular adhesion molecule-1 (ICAM-1) mediates the firm adhesion of leukocytes to endothelial cells and initiates subsequent signaling that promotes their transendothelial migration (TEM). Vascular endothelial (VE)-cadherin plays a critical role in endothelial cell–cell adhesion, thereby contro...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Yan, Meiping, Zhang, Xinhua, Chen, Ao, Gu, Wei, Liu, Jie, Ren, Xiaojiao, Zhang, Jianping, Wu, Xiaoxiong, Place, Aaron T., Minshall, Richard D., Liu, Guoquan
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636709/
https://ncbi.nlm.nih.gov/pubmed/28701303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700280R
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