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Glucagon secretion and signaling in the development of diabetes

Normal release of glucagon from pancreatic islet α-cells promotes glucose mobilization, which counteracts the hypoglycemic actions of insulin, thereby ensuring glucose homeostasis. In treatment of diabetes aimed at rigorously reducing hyperglycemia to avoid chronic complications, the resulting hypog...

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Detalhes bibliográficos
Main Authors: Gaisano, Herbert Y., MacDonald, Patrick E., Vranic, Mladen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432929/
https://ncbi.nlm.nih.gov/pubmed/22969729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00349
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