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Glucagon secretion and signaling in the development of diabetes

Normal release of glucagon from pancreatic islet α-cells promotes glucose mobilization, which counteracts the hypoglycemic actions of insulin, thereby ensuring glucose homeostasis. In treatment of diabetes aimed at rigorously reducing hyperglycemia to avoid chronic complications, the resulting hypog...

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Autors principals: Gaisano, Herbert Y., MacDonald, Patrick E., Vranic, Mladen
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432929/
https://ncbi.nlm.nih.gov/pubmed/22969729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00349
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