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SUMO1 enhances cAMP-dependent exocytosis and glucagon secretion from pancreatic α-cells
Post-translational modification by the small ubiquitin-like modifier-1 (SUMO1) limits insulin secretion from β-cells by inhibiting insulin exocytosis and glucagon-like peptide-1 (GLP-1) receptor signalling. The secretion of glucagon from α-cells is regulated in a manner opposite to that of insulin;...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4192699/ https://ncbi.nlm.nih.gov/pubmed/24907310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.274084 |
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