Six1 regulates stem cell repair potential and self-renewal during skeletal muscle regeneration

Satellite cells (SCs) are stem cells that mediate skeletal muscle growth and regeneration. Here, we observe that adult quiescent SCs and their activated descendants expressed the homeodomain transcription factor Six1. Genetic disruption of Six1 specifically in adult SCs impaired myogenic cell differ...

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Main Authors: Le Grand, Fabien, Grifone, Raphaëlle, Mourikis, Philippos, Houbron, Christophe, Gigaud, Carine, Pujol, Julien, Maillet, Marjorie, Pagès, Gilles, Rudnicki, Michael, Tajbakhsh, Shahragim, Maire, Pascal
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2012
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432771/
https://ncbi.nlm.nih.gov/pubmed/22945933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201201050
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