Six1 regulates stem cell repair potential and self-renewal during skeletal muscle regeneration

Satellite cells (SCs) are stem cells that mediate skeletal muscle growth and regeneration. Here, we observe that adult quiescent SCs and their activated descendants expressed the homeodomain transcription factor Six1. Genetic disruption of Six1 specifically in adult SCs impaired myogenic cell differ...

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Autors principals: Le Grand, Fabien, Grifone, Raphaëlle, Mourikis, Philippos, Houbron, Christophe, Gigaud, Carine, Pujol, Julien, Maillet, Marjorie, Pagès, Gilles, Rudnicki, Michael, Tajbakhsh, Shahragim, Maire, Pascal
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2012
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432771/
https://ncbi.nlm.nih.gov/pubmed/22945933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201201050
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