Six1 regulates stem cell repair potential and self-renewal during skeletal muscle regeneration

Satellite cells (SCs) are stem cells that mediate skeletal muscle growth and regeneration. Here, we observe that adult quiescent SCs and their activated descendants expressed the homeodomain transcription factor Six1. Genetic disruption of Six1 specifically in adult SCs impaired myogenic cell differ...

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Bibliographische Detailangaben
Hauptverfasser: Le Grand, Fabien, Grifone, Raphaëlle, Mourikis, Philippos, Houbron, Christophe, Gigaud, Carine, Pujol, Julien, Maillet, Marjorie, Pagès, Gilles, Rudnicki, Michael, Tajbakhsh, Shahragim, Maire, Pascal
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432771/
https://ncbi.nlm.nih.gov/pubmed/22945933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201201050
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