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Mouse ooplasm confers context-specific reprogramming capacity
Enucleated oocytes have the remarkable ability to reprogram somatic nuclei back to totipotency. Here we investigate genome-scale DNA methylation patterns after nuclear transfer and compare them to the dynamics at fertilization. We identify specific targets for DNA demethylation after nuclear transfe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432711/ https://ncbi.nlm.nih.gov/pubmed/22902786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2382 |
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