Mouse ooplasm confers context-specific reprogramming capacity

Enucleated oocytes have the remarkable ability to reprogram somatic nuclei back to totipotency. Here we investigate genome-scale DNA methylation patterns after nuclear transfer and compare them to the dynamics at fertilization. We identify specific targets for DNA demethylation after nuclear transfe...

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Detaylı Bibliyografya
Asıl Yazarlar: Chan, Michelle M., Smith, Zachary D., Egli, Dieter, Regev, Aviv, Meissner, Alexander
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432711/
https://ncbi.nlm.nih.gov/pubmed/22902786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2382
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