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DNA methylation dynamics of the human preimplantation embryo
In mammals, cytosine methylation is predominantly restricted to CpG dinucleotides and stably distributed across the genome, with local, cell type-specific regulation directed by DNA binding factors(1-3). This comparatively static landscape dramatically contrasts the events of fertilization, where th...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4178976/ https://ncbi.nlm.nih.gov/pubmed/25079558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13581 |
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