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DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos

Methylation of DNA is an essential epigenetic control mechanism in mammals. During embryonic development, cells are directed toward their future lineages, and DNA methylation poses a fundamental epigenetic barrier that guides and restricts differentiation and prevents regression into an undifferenti...

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Detalhes bibliográficos
Main Authors: Messerschmidt, Daniel M., Knowles, Barbara B., Solter, Davor
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003274/
https://ncbi.nlm.nih.gov/pubmed/24736841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.234294.113
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