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DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos
Methylation of DNA is an essential epigenetic control mechanism in mammals. During embryonic development, cells are directed toward their future lineages, and DNA methylation poses a fundamental epigenetic barrier that guides and restricts differentiation and prevents regression into an undifferenti...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4003274/ https://ncbi.nlm.nih.gov/pubmed/24736841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.234294.113 |
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