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Limb anterior-posterior polarity integrates activator and repressor functions of GLI2 as well as GLI3

Anterior-posterior (AP) limb patterning is directed by sonic hedgehog (SHH) signaling from the posteriorly located Zone of Polarizing Activity (ZPA). GLI3 and GLI2 are the transcriptional mediators generally utilized in SHH signaling, and each can function as an activator (A) and repressor (R). Alth...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Bowers, Megan, Eng, Liane, Lao, Zhimin, Turnbull, Rowena K., Bao, Xiaozhong, Riedel, Elyn, Mackem, Susan, Joyner, Alexandra L.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432687/
https://ncbi.nlm.nih.gov/pubmed/22841643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.07.017
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