Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development

The polarization of nascent embryonic fields and the endowment of cells with organizer properties are key to initiation of vertebrate organogenesis. One such event is antero-posterior (AP) polarization of early limb buds and activation of morphogenetic Sonic Hedgehog (SHH) signaling in the posterior...

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Библиографические подробности
Главные авторы: Galli, Antonella, Robay, Dimitri, Osterwalder, Marco, Bao, Xiaozhong, Bénazet, Jean-Denis, Tariq, Muhammad, Paro, Renato, Mackem, Susan, Zeller, Rolf
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851570/
https://ncbi.nlm.nih.gov/pubmed/20386744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000901
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